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Taxonomy of the updated definition and staging criteria of bacterial sepsis

Merisescu Madalina, Luminos Monica
Abstract: Sepsis can be easily defined as an exaggerated inflammatory response to a pathogen’s aggression. Due to its severity that caused increased rates of mortality, research entities mobilised impressive human and material resources in order to reach and establish rapid and safe diagnostic methods. By setting a rapid diagnosis, the proper etiologic treatment can be applied thus lowering complications and severity occurring in a sepsis case. Recently, at the Third International Consensus Definitions for Sepsis and Septic Shock held in February 2016, new scores and criteria were established in order to define and stage sepsis as accurately as possible. The new approach excludes the classical terms of systemic inflammatory response syndrome (SIRS) and includes new criteria, grounded by the PIRO concept, enabling a correct evaluation of intensive care patients, which also asses the host’s susceptibility, infection degree, response and affected organs. The objective of this study is to present the new definitions and staging criteria for bacterial sepsis and their benefitst.

Keywords: sepis, PIRO, staging, definition


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